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Detailed deletion mapping of loss of heterozygosity on 22q13 in sporadic colorectal cancer

AIM: Both development and progression of malignancies occur as a multistep process, requiring the activation of oncogenes and the inactivation of several tumor suppressor genes. The loss of heterozygosity (LOH) of tumor suppressor genes is believed to play a key role in carcinogenesis of colorectal...

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Publicado en:World J Gastroenterol
Autores principales: Zheng, Hai-Tao, Peng, Zhi-Hai, Zhou, Chong-Zhi, Li, Da-Peng, Wang, Zhao-Wen, Qiu, Guo-Qiang, He, Lin
Formato: Artigo
Lenguaje:Inglês
Publicado: Baishideng Publishing Group Inc 2005
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4305951/
https://ncbi.nlm.nih.gov/pubmed/15786547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v11.i11.1668
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