Pharmacological Targeting of Protease-Activated Receptor 2 Affords Protection from Bleomycin-Induced Pulmonary Fibrosis

Idiopathic pulmonary fibrosis is the most devastating diffuse fibrosing lung disease that remains refractory to therapy. Despite increasing evidence that protease-activated receptor 2 (PAR-2) contributes to fibrosis, its importance in pulmonary fibrosis is under debate. We addressed whether PAR-2 de...

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Pubblicato in:Mol Med
Autori principali: Lin, Cong, von der Thüsen, Jan, Daalhuisen, Joost, ten Brink, Marieke, Crestani, Bruno, van der Poll, Tom, Borensztajn, Keren, Spek, C Arnold
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Feinstein Institute Press 2015
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Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4656197/
https://ncbi.nlm.nih.gov/pubmed/26147947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2119/molmed.2015.00094
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