Loss of MeCP2 in Parvalbumin-and Somatostatin-Expressing Neurons in Mice Leads to Distinct Rett Syndrome-like Phenotypes

Inhibitory neurons are critical for proper brain function, and their dysfunction is implicated in several disorders, including autism, schizophrenia, and Rett syndrome. These neurons are heterogeneous, and it is unclear which subtypes contribute to specific neurological phenotypes. We deleted Mecp2,...

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Bibliographic Details
Published in:Neuron
Main Authors: Ito-Ishida, Aya, Ure, Kerstin, Chen, Hongmei, Swann, John W., Zoghbi, Huda Y.
Format: Artigo
Language:Inglês
Published: 2015
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4656196/
https://ncbi.nlm.nih.gov/pubmed/26590342
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2015.10.029
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