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An heuristic filtering tool to identify phenotype-associated genetic variants applied to human intellectual disability and canine coat colors

BACKGROUND: Identification of one or several disease causing variant(s) from the large collection of variants present in an individual is often achieved by the sequential use of heuristic filters. The recent development of whole exome sequencing enrichment designs for several non-model species creat...

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Bibliografiske detaljer
Udgivet i:BMC Bioinformatics
Main Authors: Broeckx, Bart J. G., Coopman, Frank, Verhoeven, Geert, Bosmans, Tim, Gielen, Ingrid, Dingemanse, Walter, Saunders, Jimmy H., Deforce, Dieter, Van Nieuwerburgh, Filip
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4656174/
https://ncbi.nlm.nih.gov/pubmed/26597515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-015-0822-7
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