Improved canine exome designs, featuring ncRNAs and increased coverage of protein coding genes

By limiting sequencing to those sequences transcribed as mRNA, whole exome sequencing is a cost-efficient technique often used in disease-association studies. We developed two target enrichment designs based on the recently released annotation of the canine genome: the exome-plus design and the exom...

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Pubblicato in:Sci Rep
Autori principali: Broeckx, Bart J.G., Hitte, Christophe, Coopman, Frank, Verhoeven, Geert E.C., De Keulenaer, Sarah, De Meester, Ellen, Derrien, Thomas, Alfoldi, Jessica, Lindblad-Toh, Kerstin, Bosmans, Tim, Gielen, Ingrid, Van Bree, Henri, Van Ryssen, Bernadette, Saunders, Jimmy H., Van Nieuwerburgh, Filip, Deforce, Dieter
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2015
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4522663/
https://ncbi.nlm.nih.gov/pubmed/26235384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep12810
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