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Cyclic RGD-targeting of reversibly-stabilized DNA nanoparticles enhances cell uptake and transfection in vitro
Reversibly-stabilized DNA nanoparticles (rSDN) were prepared by coating reducible polycation/DNA complexes with multivalent N-(2-hydroxypropyl)methacrylamide (HPMA) copolymers. RGD targeted rSDN were formulated by linking cyclic c(RGDyK) to the surface layer of rSDN. Cellular uptake in B16F10 mouse...
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| Publicado no: | J Drug Target |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4655816/ https://ncbi.nlm.nih.gov/pubmed/19263264 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/10611860902807046 |
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