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Engineering the lipid layer of lipid-PLGA hybrid nanoparticles for enhanced in vitro cellular uptake and improved stability

Lipid-polymer hybrid nanoparticles (NPs), consisting of a polymeric core and a lipid shell, have been intensively examined as delivery systems for cancer drugs, imaging agents, and vaccines. For applications in vaccine particularly, the hybrid NPs need to be able to protect the enclosed antigens dur...

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Detalhes bibliográficos
Publicado no:Acta Biomater
Main Authors: Hu, Yun, Hoerle, Reece, Ehrich, Marion, Zhang, Chenming
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4648676/
https://ncbi.nlm.nih.gov/pubmed/26428192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.actbio.2015.09.032
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