Telomeric repeat-containing RNA (TERRA) constitutes a nucleoprotein component of extracellular inflammatory exosomes

Telomeric repeat-containing RNA (TERRA) has been identified as a telomere-associated regulator of chromosome end protection. Here, we report that TERRA can also be found in extracellular fractions that stimulate innate immune signaling. We identified extracellular forms of TERRA in mouse tumor and e...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Wang, Zhuo, Deng, Zhong, Dahmane, Nadia, Tsai, Kevin, Wang, Pu, Williams, Dewight R., Kossenkov, Andrew V., Showe, Louise C., Zhang, Rugang, Huang, Qihong, Conejo-Garcia, José R., Lieberman, Paul M.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2015
Assuntos:
PNAS Plus
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4655533/
https://ncbi.nlm.nih.gov/pubmed/26578789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1505962112
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