Telomeric repeat-containing RNA (TERRA) constitutes a nucleoprotein component of extracellular inflammatory exosomes

Telomeric repeat-containing RNA (TERRA) has been identified as a telomere-associated regulator of chromosome end protection. Here, we report that TERRA can also be found in extracellular fractions that stimulate innate immune signaling. We identified extracellular forms of TERRA in mouse tumor and e...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Proc Natl Acad Sci U S A
Prif Awduron: Wang, Zhuo, Deng, Zhong, Dahmane, Nadia, Tsai, Kevin, Wang, Pu, Williams, Dewight R., Kossenkov, Andrew V., Showe, Louise C., Zhang, Rugang, Huang, Qihong, Conejo-Garcia, José R., Lieberman, Paul M.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 2015
Pynciau:
PNAS Plus
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4655533/
https://ncbi.nlm.nih.gov/pubmed/26578789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1505962112
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