Polymerase δ replicates both strands after homologous recombination-dependent fork restart

To maintain genetic stability DNA must be replicated only once and replication completed even when individual replication forks are inactivated. Because fork inactivation is common, the passive convergence of an adjacent fork is insufficient to rescue all inactive forks. Thus, eukaryotic cells have...

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Bibliografiske detaljer
Udgivet i:Nat Struct Mol Biol
Main Authors: Miyabe, Izumi, Mizuno, Ken’Ichi, Keszthelyi, Andrea, Daigaku, Yasukazu, Skouteri, Meliti, Mohebi, Saed, Kunkel, Thomas A., Murray, Johanne M., Carr, Antony M.
Format: Artigo
Sprog:Inglês
Udgivet: 2015
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4655445/
https://ncbi.nlm.nih.gov/pubmed/26436826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.3100
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