Identification of novel, therapy-responsive protein biomarkers in a mouse model of Duchenne muscular dystrophy by aptamer-based serum proteomics

There is currently an urgent need for biomarkers that can be used to monitor the efficacy of experimental therapies for Duchenne Muscular Dystrophy (DMD) in clinical trials. Identification of novel protein biomarkers has been limited due to the massive complexity of the serum proteome and the presen...

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Publicado en:Sci Rep
Main Authors: Coenen-Stass, Anna M. L., McClorey, Graham, Manzano, Raquel, Betts, Corinne A., Blain, Alison, Saleh, Amer F., Gait, Michael J., Lochmüller, Hanns, Wood, Matthew J. A., Roberts, Thomas C.
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2015
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4655324/
https://ncbi.nlm.nih.gov/pubmed/26594036
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep17014
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