The ERα-PI3K Cascade in Proopiomelanocortin Progenitor Neurons Regulates Feeding and Glucose Balance in Female Mice

Estrogens act upon estrogen receptor (ER)α to inhibit feeding and improve glucose homeostasis in female animals. However, the intracellular signals that mediate these estrogenic actions remain unknown. Here, we report that anorexigenic effects of estrogens are blunted in female mice that lack ERα sp...

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Dettagli Bibliografici
Pubblicato in:Endocrinology
Autori principali: Zhu, Liangru, Xu, Pingwen, Cao, Xuehong, Yang, Yongjie, Hinton, Antentor Othrell, Xia, Yan, Saito, Kenji, Yan, Xiaofeng, Zou, Fang, Ding, Hongfang, Wang, Chunmei, Yan, Chunling, Saha, Pradip, Khan, Sohaib A., Zhao, Jean, Fukuda, Makoto, Tong, Qingchun, Clegg, Deborah J., Chan, Lawrence, Xu, Yong
Natura: Artigo
Lingua:Inglês
Pubblicazione: Endocrine Society 2015
Soggetti:
Original Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4655219/
https://ncbi.nlm.nih.gov/pubmed/26375425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2015-1660
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