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The apparent permeabilities of Caco-2 cells to marketed drugs: magnitude, and independence from both biophysical properties and endogenite similarities

We bring together fifteen, nonredundant, tabulated collections (amounting to 696 separate measurements) of the apparent permeability (P(app)) of Caco-2 cells to marketed drugs. While in some cases there are some significant interlaboratory disparities, most are quite minor. Most drugs are not especi...

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Библиографические подробности
Опубликовано в: :PeerJ
Главные авторы: O’Hagan, Steve, Kell, Douglas B.
Формат: Artigo
Язык:Inglês
Опубликовано: PeerJ Inc. 2015
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4655101/
https://ncbi.nlm.nih.gov/pubmed/26618081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7717/peerj.1405
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