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Inflammasomes coordinate pyroptosis and natural killer cell cytotoxicity to clear infection by a ubiquitous environmental bacterium

Defective neutrophils in patients with chronic granulomatous disease (CGD) cause susceptibility to extracellular and intracellular infections. As microbes must first be ejected from intracellular niches to expose them to neutrophil attack, we hypothesized that inflammasomes detect certain CGD pathog...

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Detaylı Bibliyografya
Yayımlandı:Immunity
Asıl Yazarlar: Maltez, Vivien I., Tubbs, Alan L., Cook, Kevin D., Aachoui, Youssef, Falcone, E. Liana, Holland, Steven M., Whitmire, Jason K., Miao, Edward A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2015
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4654968/
https://ncbi.nlm.nih.gov/pubmed/26572063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2015.10.010
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