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Gas Phase Reactivity of Carboxylates with N-Hydroxysuccinimide Esters

N-hydroxysuccinimide (NHS) esters have been used for gas phase conjugation reactions with peptides at nucleophilic sites, such as primary amines (N-terminus, ε-amine of lysine) or guanidines, by forming amide bonds through a nucleophilic attack on the carbonyl carbon. The carboxylate has recently be...

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Podrobná bibliografie
Vydáno v:J Am Soc Mass Spectrom
Hlavní autoři: Peng, Zhou, McGee, William M., Bu, Jiexun, Barefoot, Nathan Z., McLuckey, Scott A.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4654944/
https://ncbi.nlm.nih.gov/pubmed/25338221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13361-014-1002-0
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