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Gas Phase Reactivity of Carboxylates with N-Hydroxysuccinimide Esters
N-hydroxysuccinimide (NHS) esters have been used for gas phase conjugation reactions with peptides at nucleophilic sites, such as primary amines (N-terminus, ε-amine of lysine) or guanidines, by forming amide bonds through a nucleophilic attack on the carbonyl carbon. The carboxylate has recently be...
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| Veröffentlicht in: | J Am Soc Mass Spectrom |
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| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4654944/ https://ncbi.nlm.nih.gov/pubmed/25338221 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13361-014-1002-0 |
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