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Matrix-derived inflammatory mediator N-acetyl proline-glycine-proline is neurotoxic and upregulated in brain after ischemic stroke

BACKGROUND: N-acetyl proline-glycine-proline (ac-PGP) is a matrix-derived chemokine produced through the proteolytic destruction of collagen by matrix metalloproteinases (MMPs). While upregulation and activation of MMPs and concomitant degradation of the extracellular matrix are known to be associat...

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Vydáno v:J Neuroinflammation
Hlavní autoři: Hill, Jeff W., Nemoto, Edwin M.
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4654865/
https://ncbi.nlm.nih.gov/pubmed/26588897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-015-0428-z
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