Matrix-derived inflammatory mediator N-acetyl proline-glycine-proline is neurotoxic and upregulated in brain after ischemic stroke

BACKGROUND: N-acetyl proline-glycine-proline (ac-PGP) is a matrix-derived chemokine produced through the proteolytic destruction of collagen by matrix metalloproteinases (MMPs). While upregulation and activation of MMPs and concomitant degradation of the extracellular matrix are known to be associat...

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Библиографические подробности
Опубликовано в: :J Neuroinflammation
Главные авторы: Hill, Jeff W., Nemoto, Edwin M.
Формат: Artigo
Язык:Inglês
Опубликовано: BioMed Central 2015
Предметы:
Short Report
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4654865/
https://ncbi.nlm.nih.gov/pubmed/26588897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-015-0428-z
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