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Modified mRNA as a new therapeutic option for pediatric respiratory diseases and hemoglobinopathies
BACKGROUND: The immunogenicity and limited stability of conventional messenger RNA (mRNA) has traditionally restricted its potential therapeutic use. In 1992, the first clinical application of mRNA was reported as a potential protein-replacement therapy; however, subsequent investigations have not b...
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Publicado no: | Mol Cell Pediatr |
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Main Authors: | , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Springer Berlin Heidelberg
2015
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4654728/ https://ncbi.nlm.nih.gov/pubmed/26589812 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40348-015-0022-6 |
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