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Cell-mediated fiber recruitment drives extracellular matrix mechanosensing in engineered fibrillar microenvironments
To investigate how cells sense stiffness in settings structurally similar to native extracellular matrices (ECM), we designed a synthetic fibrous material with tunable mechanics and user-defined architecture. In contrast to flat hydrogel surfaces, these fibrous materials recapitulated cell-matrix in...
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| Publicado no: | Nat Mater |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4654682/ https://ncbi.nlm.nih.gov/pubmed/26461445 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmat4444 |
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