Intestinal inflammation leads to a long-lasting increase in resistance to systemic salmonellosis that requires macrophages but not B or T lymphocytes at the time of pathogen challenge

BACKGROUND: Intestinal inflammation is associated with systemic translocation of commensal antigens and the consequent activation of B and T lymphocytes. The long-term consequences of such immune activation are not completely understood. METHODS: C57BL/6 mice were subjected to 2 courses of treatment...

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Veröffentlicht in:Inflamm Bowel Dis
Hauptverfasser: Trebicka, Estela, Shanmugam, Nanda Kumar N., Chen, Kejie, Su, Chien-wen, Shi, Hai Ning, Cherayil, Bobby J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4654659/
https://ncbi.nlm.nih.gov/pubmed/26222341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MIB.0000000000000544
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