IL-33 signaling protects from murine oxazolone colitis by supporting intestinal epithelial function

BACKGROUND: IL-33, a member of the IL-1 cytokine family that signals through ST2, is upregulated in ulcerative colitis (UC); however, the role of IL-33 in colitis remains unclear. IL-33 augments type 2 immune responses, which have been implicated in UC pathogenesis. We sought to determine the role o...

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Gepubliceerd in:Inflamm Bowel Dis
Hoofdauteurs: Waddell, Amanda, Vallance, Jefferson E, Moore, Preston D, Hummel, Amy T, Wu, David, Shanmukhappa, Shiva K, Fei, Lin, Washington, M Kay, Minar, Phillip, Coburn, Lori A, Nakae, Susumu, Wilson, Keith T, Denson, Lee A, Hogan, Simon P, Rosen, Michael J
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2015
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4654638/
https://ncbi.nlm.nih.gov/pubmed/26313694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MIB.0000000000000532
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