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Conditional Expression of E2A-HLF Induces B-Cell Precursor Death and Myeloproliferative-Like Disease in Knock-In Mice

Chromosomal translocations are driver mutations of human cancers, particularly leukemias. They define disease subtypes and are used as prognostic markers, for minimal residual disease monitoring and therapeutic targets. Due to their low incidence, several translocations and their biological conseque...

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Publicado en:PLoS One
Autores principales: Duque-Afonso, Jesús, Smith, Kevin S., Cleary, Michael L.
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2015
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4654581/
https://ncbi.nlm.nih.gov/pubmed/26588248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0143216
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