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Computational Model of MicroRNA Control of HIF-VEGF Pathway: Insights into the Pathophysiology of Ischemic Vascular Disease and Cancer

HRMs (hypoxia-responsive miRNAs) are a specific group of microRNAs that are regulated by hypoxia. Recent studies revealed that several HRMs including let-7 family miRNAs were highly induced in response to HIF (hypoxia-inducible factor) stabilization in hypoxia, and they potently participated in angi...

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Vydáno v:PLoS Comput Biol
Hlavní autoři: Zhao, Chen, Popel, Aleksander S.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4654485/
https://ncbi.nlm.nih.gov/pubmed/26588727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1004612
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