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Differential binding properties of [(3)H]dextrorphan and [(3)H]MK-801 in heterologously expressed NMDA receptors

The N-methyl-D-aspartate receptor (NMDAR) antagonists: MK-801, phencyclidine and ketamine are open-channel blockers with limited clinical value due to psychotomimetic effects. Similarly, the psychotomimetic effects of the dextrorotatory opioids, dextromethorphan and its metabolite dextrorphan, deriv...

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Vydáno v:Neuropharmacology
Hlavní autoři: LePage, K.T., Ishmael, J.E., Low, C.M., Traynelis, S.F., Murray, T.F.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2005
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4654417/
https://ncbi.nlm.nih.gov/pubmed/15992576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2005.01.029
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