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Quantification of miltefosine in peripheral blood mononuclear cells by high-performance liquid chromatography-tandem mass spectrometry
Phagocytes, the physiological compartment in which Leishmania parasites reside, are the main site of action of the drug miltefosine, but the intracellular pharmacokinetics of miltefosine remain unexplored. We developed a bioanalytical method to quantify miltefosine in human peripheral blood mononucl...
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| Publicado no: | J Chromatogr B Analyt Technol Biomed Life Sci |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4654404/ https://ncbi.nlm.nih.gov/pubmed/26160472 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jchromb.2015.06.017 |
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