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IL-17 induces radiation resistance of B lymphoma cells by suppressing p53 expression and thereby inhibiting irradiation-triggered apoptosis

p53 is a well-known tumor suppressor. However, the regulatory mechanism(s) for p53 expression in B lymphoma cells, and the possible role of p53 in the development of the radioresistance in tumor cells are largely unknown. A human B lymphoma cell line, Karpas1106 (k1106), was used as a model of radio...

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Publicat a:Cell Mol Immunol
Autors principals: Li, Qingshan, Xu, Xin, Zhong, Weijie, Du, Qinghua, Yu, Bizhen, Xiong, Huabao
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4654313/
https://ncbi.nlm.nih.gov/pubmed/25544504
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cmi.2014.122
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