Cardiovascular, renal and gastrointestinal effects of incretin-based therapies: an acute and 12-week randomised, double-blind, placebo-controlled, mechanistic intervention trial in type 2 diabetes

INTRODUCTION: Incretin-based therapies, that is, glucagon-like peptide (GLP)-1 receptor agonists and dipeptidyl peptidase (DPP)-4 inhibitors, are relatively novel antihyperglycaemic drugs that are frequently used in type 2 diabetes management. Apart from glucose-lowering, these agents exhibit pleiot...

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Detalhes bibliográficos
Publicado no:BMJ Open
Main Authors: Smits, Mark M, Tonneijck, Lennart, Muskiet, Marcel H A, Hoekstra, Trynke, Kramer, Mark H H, Pieters, Indra C, Cahen, Djuna L, Diamant, Michaela, van Raalte, Daniël H
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Publishing Group 2015
Assuntos:
Diabetes and Endocrinology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4654309/
https://ncbi.nlm.nih.gov/pubmed/26586327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/bmjopen-2015-009579
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