Effect of LSKL peptide on thrombospondin 1-mediated transforming growth factor β signal activation and liver regeneration after hepatectomy in an experimental model

BACKGROUND: A strategy for accelerating liver regeneration after hepatectomy would offer great benefits in preventing postoperative liver failure and improving surgical outcomes. Transforming growth factor (TGF) β is a potent inhibitor of hepatocyte proliferation. Recently, thrombospondin (TSP) 1 ha...

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Publicat a:Br J Surg
Autors principals: Kuroki, H, Hayashi, H, Nakagawa, S, Sakamoto, K, Higashi, T, Nitta, H, Hashimoto, D, Chikamoto, A, Beppu, T, Baba, H
Format: Artigo
Idioma:Inglês
Publicat: John Wiley & Sons, Ltd 2015
Matèries:
Original Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4654236/
https://ncbi.nlm.nih.gov/pubmed/25866938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bjs.9765
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