miR-9-3p plays a tumour-suppressor role by targeting TAZ (WWTR1) in hepatocellular carcinoma cells

BACKGROUND: The inactivation of the Hippo pathway lead to TAZ (PDZ-binding motif)/YAP (yes-associated protein) overexpression, and is associated with worse prognostic outcomes in various cancers including hepatocellular carcinoma (HCC). Although there are several reports of microRNA (miR) targeting...

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Bibliografske podrobnosti
izdano v:Br J Cancer
Main Authors: Higashi, T, Hayashi, H, Ishimoto, T, Takeyama, H, Kaida, T, Arima, K, Taki, K, Sakamoto, K, Kuroki, H, Okabe, H, Nitta, H, Hashimoto, D, Chikamoto, A, Beppu, T, Baba, H
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2015
Teme:
Molecular Diagnostics
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4506379/
https://ncbi.nlm.nih.gov/pubmed/26125451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2015.170
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