Adaptability at the protein-DNA interface is an important aspect of sequence recognition by bZIP proteins.

The related AP-1 and ATF/CREB families of transcriptional regulatory proteins bind as dimers to overlapping or adjacent DNA half-sites by using a bZIP structural motif. Using genetic selections, we isolated derivatives of yeast GCN4 that affect DNA-binding specificity at particular positions of the...

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Bibliographic Details
Main Authors: Kim, J, Tzamarias, D, Ellenberger, T, Harrison, S C, Struhl, K
Format: Artigo
Language:Inglês
Published: 1993
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC46542/
https://ncbi.nlm.nih.gov/pubmed/8506292
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