Adaptability at the protein-DNA interface is an important aspect of sequence recognition by bZIP proteins.

The related AP-1 and ATF/CREB families of transcriptional regulatory proteins bind as dimers to overlapping or adjacent DNA half-sites by using a bZIP structural motif. Using genetic selections, we isolated derivatives of yeast GCN4 that affect DNA-binding specificity at particular positions of the...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Kim, J, Tzamarias, D, Ellenberger, T, Harrison, S C, Struhl, K
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 1993
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC46542/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8506292/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.10.4513
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