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Structural Analysis of Substrate, Reaction Intermediate, and Product Binding in Haemophilus influenzae Biotin Carboxylase

Acetyl-CoA carboxylase catalyzes the first and regulated step in fatty acid synthesis. In most Gram-negative and Gram-positive bacteria, the enzyme is composed of three proteins: biotin carboxylase, a biotin carboxyl carrier protein (BCCP), and carboxyltransferase. The reaction mechanism involves tw...

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Bibliografske podrobnosti
izdano v:Biochemistry
Main Authors: Broussard, Tyler C., Pakhomova, Svetlana, Neau, David B., Bonnot, Ross, Waldrop, Grover L.
Format: Artigo
Jezik:Inglês
Izdano: 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4654113/
https://ncbi.nlm.nih.gov/pubmed/26020841
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.5b00340
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