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A study of whirlin isoforms in the mouse vestibular system suggests potential vestibular dysfunction in DFNB31-deficient patients

The DFNB31 gene plays an indispensable role in the cochlea and retina. Mutations in this gene disrupt its various isoforms and lead to non-syndromic deafness, blindness and deaf-blindness. However, the known expression of Dfnb31, the mouse ortholog of DFNB31, in vestibular organs and the potential v...

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Vydáno v:Hum Mol Genet
Hlavní autoři: Mathur, Pranav Dinesh, Vijayakumar, Sarath, Vashist, Deepti, Jones, Sherri M., Jones, Timothy A., Yang, Jun
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4654056/
https://ncbi.nlm.nih.gov/pubmed/26420843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddv403
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