Citral alleviates an accelerated and severe lupus nephritis model by inhibiting the activation signal of NLRP3 inflammasome and enhancing Nrf2 activation

INTRODUCTION: Lupus nephritis (LN) is a major complication of systemic lupus erythematosus. NLRP3 inflammasome activation, reactive oxygen species (ROS) and mononuclear leukocyte infiltration in the kidney have been shown to provoke the acceleration and deterioration of LN, such as accelerated and s...

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Bibliographic Details
Published in:Arthritis Res Ther
Main Authors: Ka, Shuk-Man, Lin, Jung-Chen, Lin, Tsai-Jung, Liu, Feng-Cheng, Chao, Louis Kuoping, Ho, Chen-Lung, Yeh, Li-Tzu, Sytwu, Huey-Kang, Hua, Kuo-Feng, Chen, Ann
Format: Artigo
Language:Inglês
Published: BioMed Central 2015
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4653837/
https://ncbi.nlm.nih.gov/pubmed/26584539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13075-015-0844-6
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