Citral alleviates an accelerated and severe lupus nephritis model by inhibiting the activation signal of NLRP3 inflammasome and enhancing Nrf2 activation

INTRODUCTION: Lupus nephritis (LN) is a major complication of systemic lupus erythematosus. NLRP3 inflammasome activation, reactive oxygen species (ROS) and mononuclear leukocyte infiltration in the kidney have been shown to provoke the acceleration and deterioration of LN, such as accelerated and s...

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Detalhes bibliográficos
Publicado no:Arthritis Res Ther
Main Authors: Ka, Shuk-Man, Lin, Jung-Chen, Lin, Tsai-Jung, Liu, Feng-Cheng, Chao, Louis Kuoping, Ho, Chen-Lung, Yeh, Li-Tzu, Sytwu, Huey-Kang, Hua, Kuo-Feng, Chen, Ann
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4653837/
https://ncbi.nlm.nih.gov/pubmed/26584539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13075-015-0844-6
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