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Ethosuximide Induces Hippocampal Neurogenesis and Reverses Cognitive Deficits in an Amyloid-β Toxin-induced Alzheimer Rat Model via the Phosphatidylinositol 3-Kinase (PI3K)/Akt/Wnt/β-Catenin Pathway
Neurogenesis involves generation of new neurons through finely tuned multistep processes, such as neural stem cell (NSC) proliferation, migration, differentiation, and integration into existing neuronal circuitry in the dentate gyrus of the hippocampus and subventricular zone. Adult hippocampal neur...
Guardat en:
Publicat a: | J Biol Chem |
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Autors principals: | , , , , , , , , |
Format: | Artigo |
Idioma: | Inglês |
Publicat: |
American Society for Biochemistry and Molecular Biology
2015
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Matèries: | |
Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4653709/ https://ncbi.nlm.nih.gov/pubmed/26420483 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.652586 |
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