Ethosuximide Induces Hippocampal Neurogenesis and Reverses Cognitive Deficits in an Amyloid-β Toxin-induced Alzheimer Rat Model via the Phosphatidylinositol 3-Kinase (PI3K)/Akt/Wnt/β-Catenin Pathway

Neurogenesis involves generation of new neurons through finely tuned multistep processes, such as neural stem cell (NSC) proliferation, migration, differentiation, and integration into existing neuronal circuitry in the dentate gyrus of the hippocampus and subventricular zone. Adult hippocampal neur...

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Detalles Bibliográficos
Publicado en:J Biol Chem
Autores principales: Tiwari, Shashi Kant, Seth, Brashket, Agarwal, Swati, Yadav, Anuradha, Karmakar, Madhumita, Gupta, Shailendra Kumar, Choubey, Vinay, Sharma, Abhay, Chaturvedi, Rajnish Kumar
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2015
Materias:
Neurobiology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4653709/
https://ncbi.nlm.nih.gov/pubmed/26420483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.652586
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