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Biochemical Characterization and Substrate Specificity of Autophagin-2 from the Parasite Trypanosoma cruzi

The genome of the parasite Trypanosoma cruzi encodes two copies of autophagy-related cysteine proteases, Atg4.1 and Atg4.2. T. cruzi autophagin-2 (TcAtg4.2) carries the majority of proteolytic activity and is responsible for processing Atg8 proteins near the carboxyl terminus, exposing a conserved g...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Rajković, Jelena, Poreba, Marcin, Caglič, Dejan, Vidmar, Robert, Wilk, Aleksandra, Borowik, Agata, Salvesen, Guy, Turk, Vito, Drag, Marcin, Turk, Boris
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4653680/
https://ncbi.nlm.nih.gov/pubmed/26446788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.687764
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