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Advanced Glycation End Products Affect Osteoblast Proliferation and Function by Modulating Autophagy Via the Receptor of Advanced Glycation End Products/Raf Protein/Mitogen-activated Protein Kinase/Extracellular Signal-regulated Kinase Kinase/Extracellular Signal-regulated Kinase (RAGE/Raf/MEK/ERK) Pathway

The interaction between advanced glycation end products (AGEs) and receptor of AGEs (RAGE) is associated with the development and progression of diabetes-associated osteoporosis, but the mechanisms involved are still poorly understood. In this study, we found that AGE-modified bovine serum albumin (...

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Foilsithe in:J Biol Chem
Main Authors: Meng, Hong-Zheng, Zhang, Wei-Lin, Liu, Fei, Yang, Mao-Wei
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Biochemistry and Molecular Biology 2015
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4653677/
https://ncbi.nlm.nih.gov/pubmed/26472922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.669499
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