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motifbreakR: an R/Bioconductor package for predicting variant effects at transcription factor binding sites

Summary: Functional annotation represents a key step toward the understanding and interpretation of germline and somatic variation as revealed by genome-wide association studies (GWAS) and The Cancer Genome Atlas (TCGA), respectively. GWAS have revealed numerous genetic risk variants residing in non...

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Vydáno v:Bioinformatics
Hlavní autoři: Coetzee, Simon G., Coetzee, Gerhard A., Hazelett, Dennis J.
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2015
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4653394/
https://ncbi.nlm.nih.gov/pubmed/26272984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btv470
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