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The Function of Rho-Associated Kinases ROCK1 and ROCK2 in the Pathogenesis of Cardiovascular Disease

Rho-associated kinases ROCK1 and ROCK2 are serine/threonine kinases that are downstream targets of the small GTPases RhoA, RhoB, and RhoC. ROCKs are involved in diverse cellular activities including actin cytoskeleton organization, cell adhesion and motility, proliferation and apoptosis, remodeling...

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Bibliografske podrobnosti
izdano v:Front Pharmacol
Main Authors: Hartmann, Svenja, Ridley, Anne J., Lutz, Susanne
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4653301/
https://ncbi.nlm.nih.gov/pubmed/26635606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2015.00276
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