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The Function of Rho-Associated Kinases ROCK1 and ROCK2 in the Pathogenesis of Cardiovascular Disease

Rho-associated kinases ROCK1 and ROCK2 are serine/threonine kinases that are downstream targets of the small GTPases RhoA, RhoB, and RhoC. ROCKs are involved in diverse cellular activities including actin cytoskeleton organization, cell adhesion and motility, proliferation and apoptosis, remodeling...

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Detalles Bibliográficos
Publicado en:Front Pharmacol
Main Authors: Hartmann, Svenja, Ridley, Anne J., Lutz, Susanne
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4653301/
https://ncbi.nlm.nih.gov/pubmed/26635606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2015.00276
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