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Bunched and Madm Function Downstream of Tuberous Sclerosis Complex to Regulate the Growth of Intestinal Stem Cells in Drosophila

The Drosophila adult midgut contains intestinal stem cells that support homeostasis and repair. We show here that the leucine zipper protein Bunched and the adaptor protein Madm are novel regulators of intestinal stem cells. MARCM mutant clonal analysis and cell type specific RNAi revealed that Bunc...

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Detalhes bibliográficos
Publicado no:Stem Cell Rev
Main Authors: Nie, Yingchao, Li, Qi, Amcheslavsky, Alla, Duhart, Juan Carlos, Veraksa, Alexey, Stocker, Hugo, Raftery, Laurel A., Ip, Y. Tony
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4653243/
https://ncbi.nlm.nih.gov/pubmed/26323255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12015-015-9617-5
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