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Tuberous sclerosis complex and Myc coordinate the growth and division of Drosophila intestinal stem cells

Intestinal stem cells (ISCs) in the adult Drosophila melanogaster midgut can respond to damage and support repair. We demonstrate in this paper that the tuberous sclerosis complex (TSC) plays a critical role in balancing ISC growth and division. Previous studies have shown that imaginal disc cells t...

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Bibliografske podrobnosti
Main Authors: Amcheslavsky, Alla, Ito, Naoto, Jiang, Jin, Ip, Y. Tony
Format: Artigo
Jezik:Inglês
Izdano: The Rockefeller University Press 2011
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3166862/
https://ncbi.nlm.nih.gov/pubmed/21555458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201103018
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