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Tuberous sclerosis complex and Myc coordinate the growth and division of Drosophila intestinal stem cells

Intestinal stem cells (ISCs) in the adult Drosophila melanogaster midgut can respond to damage and support repair. We demonstrate in this paper that the tuberous sclerosis complex (TSC) plays a critical role in balancing ISC growth and division. Previous studies have shown that imaginal disc cells t...

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Detalhes bibliográficos
Main Authors: Amcheslavsky, Alla, Ito, Naoto, Jiang, Jin, Ip, Y. Tony
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3166862/
https://ncbi.nlm.nih.gov/pubmed/21555458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201103018
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