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Fleeting Amyloid-like Forms of Rim4 Ensure Meiotic Fidelity

Berchowitz et al. establish that transient amyloid-like forms of Rim4, a yeast RNA-binding protein with a predicted prion domain, translationally repress cyclin CLB3 in meiosis I, thereby ensuring homologous chromosome segregation. These findings suggest that prion domains might enable formation of...

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Enregistré dans:
Détails bibliographiques
Publié dans:Cell
Auteurs principaux: Ford, Alice Flynn, Shorter, James
Format: Artigo
Langue:Inglês
Publié: 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4653133/
https://ncbi.nlm.nih.gov/pubmed/26451477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2015.09.049
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