Role for the microtubule-associated protein tau variant p.A152T in risk of α-synucleinopathies

OBJECTIVE: To assess the importance of MAPT variant p.A152T in the risk of synucleinopathies. METHODS: In this case-control study, we screened a large global series of patients and controls, and assessed associations between p.A152T and disease risk. We included 3,229 patients with clinical Parkinso...

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Publicado no:Neurology
Main Authors: Labbé, Catherine, Ogaki, Kotaro, Lorenzo-Betancor, Oswaldo, Soto-Ortolaza, Alexandra I., Walton, Ronald L., Rayaprolu, Sruti, Fujioka, Shinsuke, Murray, Melissa E., Heckman, Michael G., Puschmann, Andreas, McCarthy, Allan, Lynch, Timothy, Siuda, Joanna, Opala, Grzegorz, Rudzinska, Monika, Krygowska-Wajs, Anna, Barcikowska, Maria, Czyzewski, Krzysztof, Sanotsky, Yanosh, Rektorová, Irena, McLean, Pamela J., Rademakers, Rosa, Ertekin-Taner, Nilüfer, Hassan, Anhar, Ahlskog, J. Eric, Boeve, Bradley F., Petersen, Ronald C., Maraganore, Demetrius M., Adler, Charles H., Ferman, Tanis J., Parisi, Joseph E., Graff-Radford, Neill R., Uitti, Ryan J., Wszolek, Zbigniew K., Dickson, Dennis W., Ross, Owen A.
Formato: Artigo
Idioma:Inglês
Publicado em: Lippincott Williams & Wilkins 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4653108/
https://ncbi.nlm.nih.gov/pubmed/26333800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/WNL.0000000000001946
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