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LncRNA profiling of human lymphoid progenitors reveals transcriptional divergence of B and T lineages

To elucidate the transcriptional landscape that regulates human lymphoid commitment during postnatal life, we used RNA sequencing to assemble the long non-coding transcriptome across human bone marrow and thymic progenitors spanning the earliest stages of B and T lymphoid specification. Over 3000 no...

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Detalhes bibliográficos
Publicado no:Nat Immunol
Main Authors: Casero, David, Sandoval, Salemiz, Seet, Christopher S., Scholes, Jessica, Zhu, Yuhua, Ha, Vi Luan, Luong, Annie, Parekh, Chintan, Crooks, Gay M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4653072/
https://ncbi.nlm.nih.gov/pubmed/26502406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.3299
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