PC-1/PrLZ confers resistance to rapamycin in prostate cancer cells through increased 4E-BP1 stability

An important strategy for improving advanced PCa treatment is targeted therapies combined with chemotherapy. PC-1, a prostate Leucine Zipper gene (PrLZ), is specifically expressed in prostate tissue as an androgen-induced gene and is up-regulated in advanced PCa. Recent work confirmed that PC-1 expr...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Yu, Lan, Shang, Zeng-Fu, Wang, Jian, Wang, Hongtao, Huang, Fang, Zhang, Zhe, Wang, Ying, Zhou, Jianguang, Li, Shanhu
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4653010/
https://ncbi.nlm.nih.gov/pubmed/26011939
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