Mechanism for enhanced 5-aminolevulinic acid fluorescence in isocitrate dehydrogenase 1 mutant malignant gliomas

Fluorescence-guided surgery using 5-aminolevulinic acid (5-ALA) has become the main treatment modality in malignant gliomas. However unlike glioblastomas, there are inconsistent result about fluorescence status in WHO grade III gliomas. Here, we show that mutational status of IDH1 is linked to 5-ALA...

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Bibliografische gegevens
Gepubliceerd in:Oncotarget
Hoofdauteurs: Kim, Ja Eun, Cho, Hye Rim, Xu, Wen Jun, Kim, Ji Young, Kim, Sung Kwon, Kim, Seung-Ki, Park, Sung-Hye, Kim, Hyeonjin, Lee, Se-Hoon, Choi, Seung Hong, Park, Sunghyouk, Park, Chul-Kee
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Impact Journals LLC 2015
Onderwerpen:
Research Paper
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4653003/
https://ncbi.nlm.nih.gov/pubmed/26008980
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