Mechanism for enhanced 5-aminolevulinic acid fluorescence in isocitrate dehydrogenase 1 mutant malignant gliomas

Fluorescence-guided surgery using 5-aminolevulinic acid (5-ALA) has become the main treatment modality in malignant gliomas. However unlike glioblastomas, there are inconsistent result about fluorescence status in WHO grade III gliomas. Here, we show that mutational status of IDH1 is linked to 5-ALA...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Kim, Ja Eun, Cho, Hye Rim, Xu, Wen Jun, Kim, Ji Young, Kim, Sung Kwon, Kim, Seung-Ki, Park, Sung-Hye, Kim, Hyeonjin, Lee, Se-Hoon, Choi, Seung Hong, Park, Sunghyouk, Park, Chul-Kee
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4653003/
https://ncbi.nlm.nih.gov/pubmed/26008980
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