Phospho1 deficiency transiently modifies bone architecture yet produces consistent modification in osteocyte differentiation and vascular porosity with ageing

PHOSPHO1 is one of principal proteins involved in initiating bone matrix mineralisation. Recent studies have found that Phospho1 KO mice (Phospho1-R74X) display multiple skeletal abnormalities with spontaneous fractures, bowed long bones, osteomalacia and scoliosis. These analyses have however been...

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Bibliografski detalji
Izdano u:Bone
Glavni autori: Javaheri, B., Carriero, A., Staines, K.A., Chang, Y.-M., Houston, D.A., Oldknow, K.J., Millan, J.L., Kazeruni, Bassir N., Salmon, P., Shefelbine, S., Farquharson, C., Pitsillides, A.A.
Format: Artigo
Jezik:Inglês
Izdano: Elsevier Science 2015
Teme:
Original Full Length Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4652607/
https://ncbi.nlm.nih.gov/pubmed/26232374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bone.2015.07.035
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