Phospho1 deficiency transiently modifies bone architecture yet produces consistent modification in osteocyte differentiation and vascular porosity with ageing

PHOSPHO1 is one of principal proteins involved in initiating bone matrix mineralisation. Recent studies have found that Phospho1 KO mice (Phospho1-R74X) display multiple skeletal abnormalities with spontaneous fractures, bowed long bones, osteomalacia and scoliosis. These analyses have however been...

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Sparad:
Bibliografiska uppgifter
I publikationen:Bone
Huvudupphovsmän: Javaheri, B., Carriero, A., Staines, K.A., Chang, Y.-M., Houston, D.A., Oldknow, K.J., Millan, J.L., Kazeruni, Bassir N., Salmon, P., Shefelbine, S., Farquharson, C., Pitsillides, A.A.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Elsevier Science 2015
Ämnen:
Original Full Length Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4652607/
https://ncbi.nlm.nih.gov/pubmed/26232374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bone.2015.07.035
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