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Olfactomedin 4 deficiency promotes prostate neoplastic progression and is associated with upregulation of the hedgehog-signaling pathway

Loss of olfactomedin 4 (OLFM4) gene expression is associated with the progression of human prostate cancer, but its role and the molecular mechanisms involved in this process have not been completely understood. In this study, we found that Olfm4-knockout mice developed prostatic intraepithelial neo...

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Podrobná bibliografie
Vydáno v:Sci Rep
Hlavní autoři: Li, Hongzhen, Liu, Wenli, Chen, Weiping, Zhu, Jianqiong, Deng, Chu-Xia, Rodgers, Griffin P.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4652203/
https://ncbi.nlm.nih.gov/pubmed/26581960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep16974
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